From mid-September to mid-May, the Murie Science Learning Center serves as Denali National Park's winter visitors' center. It's open from 9am to 4pm and provides an array of park exhibits and movies. You can talk with rangers about current trail conditions, borrow a pair of snowshoes, and get backcountry permits for overnight trips. Head out to explore trails from the center or drive a couple miles further up the park road to the Park Headquarters before starting your adventure. The park road is closed from mile 3.2 and beyond, but it makes for excellent skiing, snowshoeing and hiking. The one plus to leaving your car at the MSLC is the fact that they have outdoor electrical outlets where you can plug in your vehicle when the temperatures plummet.
For shelter from the cold, the entryway at the MSLC and the Post Office near the entrance of the park are open around the clock.